CEMIP2 Antibodies

AND CEMIP2 ELISA kits, CEMIP2 Proteins

Many biological assays use antibodies to detect CEMIP2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CEMIP2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CEMIP2 antibodies...

We validate the specificity of these antibodies to CEMIP2 by testing them on tissues known to express CEMIP2 positively and negatively. Browse below to find the CEMIP2 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: SEPTIN9 Next: STX12

CEMIP2 Infographic by Boster Bio

All CEMIP2 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

CEMIP2 Overview

Facts about Cell surface hyaluronidase.

CEMIP2 3D structure. Source: alphafold

Cell surface hyaluronidase (CEMIP2)

Cell surface hyaluronidase that mediates the initial cleavage of extracellular high-molecular-weight hyaluronan into intermediate-size hyaluronan of approximately 5 kDa fragments (PubMed:28246172). Acts as a regulator of angiogenesis and heart morphogenesis by mediating degradation of extracellular hyaluronan, thereby regulating VEGF signaling (By similarity).

Is very specific to hyaluronan; not able to cleave chondroitin sulfate or dermatan sulfate (PubMed:28246172). .

Gene Information

Human
Gene Name:	CEMIP2
Uniprot:	Q9UHN6
Entrez:	23670

Family

Belongs to:

CEMIP family

Alternative Names

Cell surface hyaluronidase

Molecular Weight

Mass (kDA):
154.374 kDA

Genomic Context


Human

Location:	9q21.13
Sequence:	9; NC_000009.12 (71683366..71769532, complement)

Tissue Specificity

Widely expressed.

Subcellular Localizations

Cell membrane; Single-pass type II membrane protein.

PTMs

Glycoprotein

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CEMIP2

References

PMID: 10767548 by Scott D.A., et al. Refining the DFNB7-DFNB11 deafness locus using intragenic polymorphisms in a novel gene, TMEM2.

PMID: 28246172 by Yamamoto H., et al. A Mammalian homolog of the zebrafish transmembrane protein 2 (TMEM2) is the long-sought-after cell surface hyaluronidase.