Cbp/p300-interacting transactivator 1 (CITED1)

Transcriptional coactivator of the p300/CBP-mediated transcription complex. Enhances SMAD-mediated transcription by strengthening the operational link between the DNA-binding SMAD transcription factors and the p300/CBP transcription coactivator complex.

Stimulates estrogen-dependent transactivation activity mediated by estrogen receptors signaling; stabilizes the interaction of nitric oxide ESR1 and histone acetyltransferase EP300. Induces transcription from estrogen-responsive promoters and protection against cell death.