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- Table of Contents
CITED1 Antibodies
AND CITED1 ELISA kits, CITED1 Proteins
Many biological assays use antibodies to detect CITED1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CITED1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CITED1 antibodies...
Designing a Western blot for CITED1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CITED1 Western Blot GuideCITED1 Infographic by Boster Bio
All CITED1 Products
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CITED1 Overview
Facts about Cbp/p300-interacting transactivator 1.
Cbp/p300-interacting transactivator 1 (CITED1)
Transcriptional coactivator of the p300/CBP-mediated transcription complex. Enhances SMAD-mediated transcription by strengthening the operational link between the DNA-binding SMAD transcription factors and the p300/CBP transcription coactivator complex.
Stimulates estrogen-dependent transactivation activity mediated by estrogen receptors signaling; stabilizes the interaction of nitric oxide ESR1 and histone acetyltransferase EP300. Induces transcription from estrogen-responsive promoters and protection against cell death.
Gene Information
| Human | |
|---|---|
| Gene Name: | CITED1 |
| Uniprot: | Q99966 |
| Entrez: | 4435 |
Family
| Belongs to: |
|---|
| CITED family |
Alternative Names
cbp/p300-interacting transactivator 1; Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain1,MSG1Melanocyte-specific protein 1; melanocyte-specific gene 1
Molecular Weight
Mass (kDA):
19.896 kDA
Genomic Context
| Human | |
|---|---|
| Location: | Xq13.1 |
| Sequence: | X; NC_000023.11 (72301638..72307157, complement) |
Tissue Specificity
Expressed only in melanocytes and testis.
Subcellular Localizations
Nucleus. Cytoplasm. Shuttles between the nucleus and the cytoplasm by a nuclear export signal and (NES) in a CRM1-dependent manner.
Diseases
- Neoplasms
- Carcinoma
- Malignant Neoplasms
- Thyroid Neoplasm
- Malignant Neoplasm Of Thyroid
- Papillary Thyroid Carcinoma
- Malignant Paraganglionic Neoplasm
- Melanoma
- Adenoma
- Nephroblastoma
- Carcinoma, Papillary
- Follicular Adenoma
- Neoplasm Metastasis
Interacting Proteins
- ATF2
- ESR1
- JUN
Pathways
- Cell Cycle
- Pigmentation
- Gastrulation
- Methylation
- Pathogenesis
- Oncogenesis
- Cell Proliferation
- Localization
- Cell Death
- Kidney Development
- Dna Hypermethylation
- Mammary Gland Development
- Nuclear Export
PTMs
- Methylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CITED1
bosterbio.com/bosterbio-gene-info-cards/CITED1
References
PMID: 8901575 by Shioda T., et al. msg1, a novel melanocyte-specific gene, encodes a nuclear protein and is associated with pigmentation.
PMID: 9707553 by Shioda T., et al. Transcriptional activating activity of Smad4: roles of SMAD hetero- oligomerization and enhancement by an associating transactivator.