CLIP-associating protein 1 (CLASP1)

Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN).

Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the top edge of the cell. May act in the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2.