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Clk4 Antibodies

AND Clk4 ELISA kits, Clk4 Proteins

Many biological assays use antibodies to detect Clk4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Clk4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Clk4 antibodies...

We validate the specificity of these antibodies to Clk4 by testing them on tissues known to express Clk4 positively and negatively. Browse below to find the Clk4 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Clk4 Infographic by Boster Bio

Clk4 protein infographic

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Anti-CLK4 Antibody

Western Blot analysis of various cells using CLK4 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit

Western Blot analysis of various cells using CLK4 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit

Western blot analysis of lysates from HT-29 cells, using CLK4 Antibody

Western blot analysis of the lysates from HeLa cells using CLK4 antibody

Human, Mouse

ELISA, IF, IHC, WB

$380
Cat # A09141-1
100ul

Clk4 Overview

Facts about Dual specificity protein kinase CLK4.

Dual specificity protein kinase CLK4 (Clk4)

Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex and may be a part of a network of regulatory mechanisms that enable SR proteins to control RNA splicing.

Phosphorylates SRSF1 and SRSF3. Required for the regulation of alternative splicing of MAPT/TAU.

Gene Information

Mouse
Gene Name:	Clk4
Uniprot:	O35493
Entrez:	12750

Gene Information

Family

Belongs to:

protein kinase superfamily

Family

Alternative Names

CDC-like kinase 4EC 2.7.12.1; DKFZp686A20267; dual specificity protein kinase CLK4; protein serine threonine kinase Clk4

Molecular Weight

Mass (kDA):
57.345 kDA

Molecular Weight

Genomic Context


Mouse

Location:	11\|11 B1.3
Sequence:	11;

Tissue Specificity

Expressed in the hippocampus, the cerebellum and the olfactory bulb.

Diseases

Acute Erythroblastic Leukemia
Malignant Neoplasms
Obesity
Neurodegenerative Disorders
Pituitary Diseases
Dwarfism
Malignant Tumor Of Colon

Genotoxic Stress

Disease

Pathways

Response To Oxidative Stress
Bioluminescence
Circadian Behavior
Cell Differentiation
Dna Repair
Cell Growth

Localization

Pathways

PTMs

Phosphorylation

Dephosphorylation

Research Areas

Protein Kinase

Research Areas

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Clk4

References

PMID: 9307018 by Nayler O., et al. Characterization and comparison of four serine- and arginine-rich (SR) protein kinases.

PMID: 9339371 by Watkins-Chow D.E., et al. Construction of a 3-Mb contig and partial transcript map of the central region of mouse chromosome 11.