Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 Info At a glance, species: Human
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Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 (CMTR1)
S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 two'-O-ribose methylation into the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) to produce m(7)GpppRm (cap1).
Displays a preference for cap0 transcripts. Cap1 modification is connected to high levels of translation.
Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1
|Sequence:||6; NC_000006.12 (37433214..37482844)|