CNTNAP2 Antibodies

AND CNTNAP2 ELISA kits, CNTNAP2 Proteins

Many biological assays use antibodies to detect CNTNAP2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CNTNAP2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CNTNAP2 antibodies...

We validate the specificity of these antibodies to CNTNAP2 by testing them on tissues known to express CNTNAP2 positively and negatively. Browse below to find the CNTNAP2 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for CNTNAP2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the CNTNAP2 Western Blot Guide

CNTNAP2 Infographic by Boster Bio

All CNTNAP2 Products

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Specificity

Applications

Price

Human CASPR2 ELISA Kit PicoKine®

Human

ELISA

$499
Cat # EK2169
96 wells/kit, with removable strips.

Anti-CNTP2 Rabbit Monoclonal Antibody

All lanes use the Antibody at 1:3K dilution for 1 hour at room temperature

All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature

Human, Mouse, Rat

IHC, WB

$370
Cat # M02819
100 μl/vial

Anti-Caspr2/CNTNAP2 Antibody Picoband®

Western blot analysis of Caspr2/CNTNAP2 using anti-Caspr2/CNTNAP2 antibody (A02819-2)

Human, Mouse, Rat

ELISA, WB

$370
Cat # A02819-2
100 µg/vial

Caspr2 (CNTNAP2) (NM_014141) Human Over-expression Lysate

Human

$628
Cat # LS026047
20 µg, 100 µg

CNTNAP2 Overview

Facts about Contactin-associated protein-like 2.

CNTNAP2 3D structure. Source: alphafold

Contactin-associated protein-like 2 (CNTNAP2)

Required, with CNTNAP1, for radial and longitudinal organization of myelinated axons. Plays a role in the formation of functional different domains essential for saltatory conduction of nerve impulses in myelinated nerve fibers.

Demarcates the juxtaparanodal region of the axo-glial junction. .

Gene Information

Human
Gene Name:	CNTNAP2
Uniprot:	Q9UHC6
Entrez:	26047

Family

Belongs to:

neurexin family

Alternative Names

AUTS15; Caspr2; CASPR2DKFZp781D1846; CDFE; Cell recognition molecule Caspr2; CNTNAP2; contactin associated protein-like 2; contactin-associated protein 2; contactin-associated protein-like 2; homolog of Drosophila neurexin IV; KIAA0868; NRXN4; NRXN4Caspr2; PTHSL1

Molecular Weight

Mass (kDA):
148.167 kDA

Genomic Context


Human

Location:	7q35-q36.1
Sequence:	7; NC_000007.14 (146116207..148420998)

Tissue Specificity

Predominantly expressed in nervous system.

Subcellular Localizations

Membrane; Single-pass type I membrane protein. Cell projection, axon. Cell junction, paranodal septate junction. Expressed in the juxtaparadonal region.

Diseases

Autistic Disorder
Language Disorders
Autism Spectrum Disorders
Epilepsy
Tissue Adhesions
Schizophrenia
Specific Language Impairment
Child Development Disorders, Pervasive
Neoplasms
Nervousness
Language Development Disorders
Malignant Neoplasms

Isaacs Syndrome
Encephalitis
Language Delays
Gilles De La Tourette Syndrome
Autoimmune Diseases
Attention Deficit Hyperactivity Disorder

Interacting Proteins

CANX
CNTN1
MEOX2

Pathways

Localization
Cell Adhesion
Pathogenesis
Methylation
Brain Development
Synaptic Transmission
Myelination
System Development
Axon Guidance
Nervous System Development
Cognition
Cell Migration

Cellular Homeostasis
Cell Development
Immune Response
Dna Methylation
Endocytosis
Vocal Learning
Metabolic Process

PTMs

Methylation

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CNTNAP2

References

PMID: 10624965 by Poliak S., et al. Caspr2, a new member of the neurexin superfamily, is localized at the juxtaparanodes of myelinated axons and associates with K+ channels.

PMID: 11352571 by Nakabayashi K., et al. The human contactin-associated protein-like 2 gene (CNTNAP2) spans over 2 Mb of DNA at chromosome 7q35.

1 Publications of Boster CNTNAP2 Antibodies & ELISA Kits

PubMed ID: 10.3892/etm.2017.4228, Alterations of Caspr2 and Nav1.6 on myelinated axon damage in a rat model of chr...

*More publications can be found for each product on its corresponding product page