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- Table of Contents
Commd1 Antibodies
AND Commd1 ELISA kits, Commd1 Proteins
Many biological assays use antibodies to detect Commd1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Commd1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Commd1 antibodies...
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Commd1 Infographic by Boster Bio
All Commd1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IHC, WB
$523
Cat # M02272
100 µl
Cat # M02272
100 µl
Dog, Human, Monkey, Mouse, Rat
Flow Cytometry, IHC, WB
$523
Cat # M02272-1
100 µl
Cat # M02272-1
100 µl
Human, Mouse, Rat
Flow Cytometry, IF, IHC, WB
$523
Cat # M02272-2
100 µl
Cat # M02272-2
100 µl
Commd1 Overview
Facts about COMM domain-containing protein 1.
COMM domain-containing protein 1 (Commd1)
Proposed scaffold protein that is implicated in diverse physiological processes and whose function may be in part linked to its ability to regulate ubiquitination of specific cellular proteins. Can modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes by displacing CAND1; in vitro boosts CRL E3 activity and dissociates CAND1 from CUL1 and CUL2.
Promotes ubiquitination of NF-kappa-B subunit RELA and its subsequent proteasomal degradation. Down-regulates NF-kappa-B activity.
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Commd1 |
| Uniprot: | Q8K4M5 |
| Entrez: | 17846 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
C2orf5; COMM domain-containing protein 1; COMMD1; copper metabolism (Murr1) domain containing 1; copper metabolism gene MURR1; MGC27155; MURR1; MURR1chromosome 2 open reading frame 5 (MURR1); Protein Murr1
Molecular Weight
Mass (kDA):
20.996 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 11 A3.2|11 14.22 cM |
| Sequence: | 11; |
Diseases
- Poisoning Syndrome
- Hepatolenticular Degeneration
- Dog Diseases
- Neoplasms
- Liver Cirrhosis
- Menkes Kinky Hair Syndrome
- Malignant Neoplasms
- Copper Deficiency
- Hiv Infections
- Fibrosis
- Copper Metabolism Disorder
- Liver Diseases
Pathways
- Transport
- Excretion
- Localization
- Proteolysis
- Methylation
- Cell Death
- Pathogenesis
- Cell Cycle
- Oncogenesis
- Regulation Of Cell Death
- Cell Proliferation
- Dna Methylation
- Protein Folding
PTMs
- Ubiquitination
- Phosphorylation
- Methylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Commd1
bosterbio.com/bosterbio-gene-info-cards/Commd1
References
PMID: 14673161 by Wang Y., et al. The mouse Murr1 gene is imprinted in the adult brain, presumably due to transcriptional interference by the antisense-oriented U2af1-rs1 gene.
1 Publications of Boster Commd1 Antibodies & ELISA Kits
- PubMed ID: 10.1371/journal.pgen.1007890, Genes encoding SATB2-interacting proteins in adult cerebral cortex contribute to...
*More publications can be found for each product on its corresponding product page