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- Table of Contents
Facts about Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial.
The electrons required for the hydroxylation reaction might be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. .
| Human | |
|---|---|
| Gene Name: | COQ6 |
| Uniprot: | Q9Y2Z9 |
| Entrez: | 51004 |

| Belongs to: |
|---|
| UbiH/COQ6 family |

CGI-10; coenzyme Q6 homolog (yeast); coenzyme Q6 homolog, monooxygenase (S. cerevisiae); coenzyme Q6 homolog, monooxygenase (yeast); EC 1.14.13; EC 1.14.13.-; ubiquinone biosynthesis monooxygenase COQ6
Mass (kDA):
50.87 kDA

| Human | |
|---|---|
| Location: | 14q24.3 |
| Sequence: | 14; NC_000014.9 (73949934..73963670) |
Widely expressed.
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side. Golgi apparatus. Cell projection. Localizes to cell processes and Golgi apparatus in podocytes.





PMID: 24270420 by Ashraf S., et al. ADCK4 mutations promote steroid-resistant nephrotic syndrome through CoQ10 biosynthesis disruption.
PMID: 26260787 by Ozeir M., et al. Coq6 is responsible for the C4-deamination reaction in coenzyme Q biosynthesis in Saccharomyces cerevisiae.