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- Table of Contents
Facts about Cytoplasmic polyadenylation element-binding protein 3.
Required for the consolidation and maintenance of hippocampal-based long term memory (By similarity). Also represses the translation of DLG4, GRIN1, GRIN2A and GRIN2B (By similarity).
| Human | |
|---|---|
| Gene Name: | CPEB3 |
| Uniprot: | Q8NE35 |
| Entrez: | 22849 |

| Belongs to: |
|---|
| RRM CPEB family |

CPE-binding protein 3; cytoplasmic polyadenylation element binding protein 3; cytoplasmic polyadenylation element-binding protein 3; hCPEB-3; KIAA0940CPE-BP3
Mass (kDA):
76.014 kDA

| Human | |
|---|---|
| Location: | 10q23.32 |
| Sequence: | 10; NC_000010.11 (92046692..92291499, complement) |
Cytoplasm. Nucleus. Cell junction, synapse. Cell projection, dendrite. Cell junction, synapse, postsynaptic density. Predominantly cytoplasmic in unstimulated neurons but translocates to the nucleus following neuronal stimulation (PubMed:20639532, PubMed:22730302). Nuclear import is mediated by importin IPO5 (By similarity).





PMID: 16990549 by Salehi-Ashtiani K., et al. A genomewide search for ribozymes reveals an HDV-like sequence in the human CPEB3 gene.
PMID: 19503753 by Vogler C., et al. CPEB3 is associated with human episodic memory.