CTD nuclear envelope phosphatase 1 (CTDNEP1)

Serine/threonine protein phosphatase forming CNEP1R1 an active phosphatase complex that dephosphorylates and may activate LPIN1 and LPIN2. LPIN1 and LPIN2 are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels.

May indirectly modulate the lipid composition of atomic and/or endoplasmic reticulum membranes and also be required for proper nuclear membrane morphology and/or dynamics. May also indirectly regulate the production of lipid droplets and triacylglycerol.