Cytochrome b5 reductase 4 Antibodies

AND CYB5R4 ELISA kits, Cytochrome b5 reductase 4 Proteins

Many biological assays use antibodies to detect Cytochrome b5 reductase 4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cytochrome b5 reductase 4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cytochrome b5 reductase 4 antibodies...

We validate the specificity of these antibodies to Cytochrome b5 reductase 4 by testing them on tissues known to express CYB5R4 positively and negatively. Browse below to find the CYB5R4 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CYB5R4 Infographic by Boster Bio

All CYB5R4 Products

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Specificity

Applications

Price

Anti-NB5R4 CYB5R4 Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A13361
100ul

CYB5R4 (NM_016230) Human Recombinant Protein

Coomassie blue staining of purified CYB5R4 protein

$1249
Cat # PROTQ7L1T6
20 µg

CYB5R4 (NM_016230) Human Over-expression Lysate

Human

$628
Cat # LS051167
20 µg, 100 µg

CYB5R4 Overview

Facts about Cytochrome b5 reductase 4.

CYB5R4 3D structure. Source: alphafold

Cytochrome b5 reductase 4 (CYB5R4)

NADH-cytochrome b5 reductase involved in endoplasmic reticulum stress response pathway. Plays a crucial role in protecting pancreatic beta-cells against oxidant stress, possibly by protecting the cell from excess buildup of reactive oxygen species (ROS).

Reduces a variety of substrates in vitro, such as cytochrome c, feericyanide and methemoglobin. .

Gene Information

Human
Gene Name:	CYB5R4
Uniprot:	Q7L1T6
Entrez:	51167

Family

Belongs to:

flavoprotein pyridine nucleotide cytochrome reductase family

Alternative Names

b5+b5R; cb5/cb5R; cytochrome b5 reductase 4; cytochrome b-type NAD(P)H oxidoreductase; dJ676J13.1; EC 1.6.2.2; Flavohemoprotein b5/b5R; flavohemoprotein b5+b5R; NADPH cytochrome B5 oxidoreductase; NCB5ORN-terminal cytochrome b5 and cytochrome b5 oxidoreductase domain-containingprotein; RP4-676J13.1

Molecular Weight

Mass (kDA):
59.474 kDA

Genomic Context


Human

Location:	6q14.2
Sequence:	6; NC_000006.12 (83859689..83967423)

Tissue Specificity

Widely expressed.

Subcellular Localizations

Endoplasmic reticulum. Soluble protein.

PTMs

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CYB5R4

References

PMID: 10611283 by Zhu H., et al. Identification of a cytochrome b-type NAD(P)H oxidoreductase ubiquitously expressed in human cells.

PMID: 20630863 by Deng B., et al. Study of the individual cytochrome b5 and cytochrome b5 reductase domains of Ncb5or reveals a unique heme pocket and a possible role of the CS domain.