Cytochrome P450 2A4 Antibodies

AND Cyp2a4 ELISA kits, Cytochrome P450 2A4 Proteins

Many biological assays use antibodies to detect Cytochrome P450 2A4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cytochrome P450 2A4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cytochrome P450 2A4 antibodies...

We validate the specificity of these antibodies to Cytochrome P450 2A4 by testing them on tissues known to express Cyp2a4 positively and negatively. Browse below to find the Cyp2a4 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Cyp2a4 Infographic by Boster Bio

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Cyp2a4 Overview

Facts about Cytochrome P450 2A4.

Cyp2a4 3D structure. Source: alphafold

Cytochrome P450 2A4 (Cyp2a4)

Highly active in the 15-alpha-hydroxylation of testosterone. Also active in the 15-alpha-hydroxylation of progesterone and androstenedione.

Little or no action on corticosterone, pregnenolone, dehydroepiandrosterone, estradiol or estriol. .

Gene Information

Mouse
Gene Name:	Cyp2a4
Uniprot:	P15392
Entrez:	13086

Family

Belongs to:

cytochrome P450 family

Alternative Names

Cytochrome P450 2A4

Molecular Weight

Mass (kDA):
56.782 kDA

Genomic Context


Mouse

Location:	7 A3\|7 14.39 cM
Sequence:	7;

Tissue Specificity

Kidney and lung. Expressed in liver, with a strong circadian rhythmicity. Circadian expression is regulated by DBP.

PTMs

Acetylation

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Cyp2a4

References

PMID: 2703500 by Lindberg R., et al. The structure and characterization of type I P-450(15) alpha gene as major steroid 15 alpha-hydroxylase and its comparison with type II P- 450(15) alpha gene.

PMID: 3346244 by Squires E.J., et al. Reciprocal regulation of sex-dependent expression of testosterone 15 alpha-hydroxylase (P-450(15 alpha)) in liver and kidney of male mice by androgen. Evidence for a single gene.