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- Table of Contents
Facts about Cytosolic iron-sulfur assembly component 2B.
Included in the mitotic spindle- associated MMXD complicated it plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD (PubMed:20797633). .
| Human | |
|---|---|
| Gene Name: | CIAO2B |
| Uniprot: | Q9Y3D0 |
| Entrez: | 51647 |

| Belongs to: |
|---|
| MIP18 family |

Cytosolic iron-sulfur assembly component 2B
Mass (kDA):
17.663 kDA

| Human | |
|---|---|
| Location: | 16q22.1 |
| Sequence: | 16; NC_000016.10 (66932065..66934402, complement) |
Nucleus. Cytoplasm, cytoskeleton, spindle.



PMID: 20797633 by Ito S., et al. MMXD, a TFIIH-independent XPD-MMS19 protein complex involved in chromosome segregation.
PMID: 22678362 by Stehling O., et al. MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity.