Contactin-6 Antibodies

AND CNTN6 ELISA kits, Contactin-6 Proteins

Many biological assays use antibodies to detect Contactin-6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Contactin-6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Contactin-6 antibodies...

We validate the specificity of these antibodies to Contactin-6 by testing them on tissues known to express CNTN6 positively and negatively. Browse below to find the CNTN6 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CNTN6 Infographic by Boster Bio

All CNTN6 Products

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Specificity

Applications

Price

Mouse Contactin-6 ELISA Kit PicoKine®

7 Q&As

Mouse

ELISA

$750
Cat # EK1783
96 wells/kit, with removable strips.

Anti-Contactin 6 CNTN6 Antibody

Western blot analysis of the lysates from HeLa cells using CNTN6 antibody

Human, Mouse

ELISA, WB

$380
Cat # A07585
100ul

CNTN6 (NM_014461) Human Over-expression Lysate

Human

$960
Cat # LS027255
20 µg, 100 µg

CNTN6 Overview

Facts about Contactin-6.

CNTN6 3D structure. Source: alphafold

Contactin-6 (CNTN6)

Contactins mediate cell surface interactions during nervous system development. Participates in oligodendrocytes creation by acting as a ligand of NOTCH1.

Its association with NOTCH1 boosts NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Involved in motor coordination (By similarity).

Gene Information

Human
Gene Name:	CNTN6
Uniprot:	Q9UQ52
Entrez:	27255

Family

Belongs to:

immunoglobulin superfamily

Alternative Names

CNTN6; contactin 6; Contactin6; Contactin-6; MGC133256; NB3

Molecular Weight

Mass (kDA):
113.956 kDA

Genomic Context


Human

Location:	3p26.3
Sequence:	3; NC_000003.12 (978021..1404217)

Tissue Specificity

Expressed in nervous system. Highly expressed in cerebellum. Expressed at intermediate level in thalamus, subthalamic nucleus. Weakly expressed in corpus callosum, caudate nucleus and spinal cord.

Subcellular Localizations

Cell membrane; Lipid-anchor, GPI-anchor.

Diseases

Tissue Adhesions
Malignant Neoplasms
Nervousness
Mental Disorders
Malignant Neoplasm Of Prostate
Autistic Disorder
Autism Spectrum Disorders
Hepatitis B
Sensation Disorders
Malignant Neoplasm Of Liver

Carcinoma
Neoplasms
Malignant Neoplasm Of Ovary
Ovarian Neoplasm
Bipolar Disorder

Pathways

Cell Adhesion
Localization
Cell Differentiation
Cellular Response To Dsrna
Brain Development
Response To Dsrna
Reverse Transcription
Erbb Signaling Pathway
T Cell Differentiation
Cell Cycle
Dsrna Fragmentation

Cell Communication
Catabolic Process
Pathogenesis
Oligodendrocyte Development
Ncrna Catabolic Process

PTMs

Disulfide bond
Glycoprotein

GPI-anchor
Lipoprotein

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CNTN6

References

PMID: 9486763 by Kamei Y., et al. cDNA cloning and chromosomal localization of neural adhesion molecule, NB-3 in human.

PMID: 20133774 by Bouyain S., et al. The protein tyrosine phosphatases PTPRZ and PTPRG bind to distinct members of the contactin family of neural recognition molecules.