Cops7b Antibodies

AND Cops7b ELISA kits, Cops7b Proteins

Many biological assays use antibodies to detect Cops7b, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cops7b in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cops7b antibodies...

We validate the specificity of these antibodies to Cops7b by testing them on tissues known to express Cops7b positively and negatively. Browse below to find the Cops7b antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for Cops7b? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the COPS7B IHC Guide

Cops7b Infographic by Boster Bio

All Cops7b Products

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Product

Figures

Specificity

Applications

Price

Anti-COPS7B Antibody (N-Term)

Overlay histogram showing Hela cells stained with M12717 (green line)

Human

Flow Cytometry, IHC-P, WB

$299
Cat # M12717
50 µl

CSN7b (COPS7B) (NM_022730) Human Over-expression Lysate

Human

$628
Cat # LS064708
20 µg, 100 µg

Cops7b Overview

Facts about COP9 signalosome complex subunit 7b.

COP9 signalosome complex subunit 7b (Cops7b)

Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2.

The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively (By similarity).

Gene Information

Mouse
Gene Name:	Cops7b
Uniprot:	Q8BV13
Entrez:	26895

Family

Belongs to:

CSN7/EIF3M family

Alternative Names

Arabidopsis, homolog) subunit 7B; COP9 constitutive photomorphogenic homolog subunit 7B (Arabidopsis); COP9 signalosome complex subunit 7b; CSN7BMGC111077; FLJ12612; Signalosome subunit 7b

Molecular Weight

Mass (kDA):
29.689 kDA

Genomic Context


Mouse

Location:	1 C5\|1 43.97 cM
Sequence:	1;

PTMs

Acetylation

Research Areas

Growth and Development
Neuronal Cell Markers
Neurotransmission
Signal Transduction
Transcription Factors and Regulators

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Cops7b

References

PMID: 9707402 by Wei N., et al. The COP9 complex is conserved between plants and mammals and is related to the 26S proteasome regulatory complex.