Protocadherin-16 Antibodies

AND DCHS1 ELISA kits, Protocadherin-16 Proteins

Many biological assays use antibodies to detect Protocadherin-16, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protocadherin-16 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protocadherin-16 antibodies...

We validate the specificity of these antibodies to Protocadherin-16 by testing them on tissues known to express DCHS1 positively and negatively. Browse below to find the DCHS1 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DCHS1 Infographic by Boster Bio

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DCHS1 Overview

Facts about Protocadherin-16.

Protocadherin-16 (DCHS1)

Calcium-dependent cell-adhesion protein. Mediates works in neuroprogenitor cell proliferation and differentiation.

In the center, has a important function for proper morphogenesis of the mitral valve, behaving in the regulation of cell migration involved in valve formation (PubMed:26258302). .

Gene Information

Human
Gene Name:	DCHS1
Uniprot:	Q96JQ0
Entrez:	8642

Family

Belongs to:

No superfamily

Alternative Names

protocadherin-16; CDH25; CDHR6; dachsous 1 (Drosophila); FIB1; PCDH16

Molecular Weight

Mass (kDA):
346.181 kDA

Genomic Context


Human

Location:	11p15.4
Sequence:	11; NC_000011.10 (6621330..6655809, complement)

Tissue Specificity

Expressed in fibroblasts but not in melanocytes or keratinocytes.

Subcellular Localizations

Cell membrane; Single-pass type I membrane protein. In the embryonic cortex, FAT4 and DCHS1 accumulated at the cell-cell boundaries located apical to the adherens junction.

Diseases

Van Maldergem syndrome 1 (VMLDS1)

Pathways

Membrane Organization
Plasma Membrane Organization
Kidney Development

PTMs

Glycoprotein

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DCHS1

References

PMID: 11597768 by Nakajima D., et al. Identification of three novel non-classical cadherin genes through comprehensive analysis of large cDNAs.

PMID: 9199196 by Matsuyoshi N., et al. Multiple cadherins are expressed in human fibroblasts.