Dynactin subunit 3 Antibodies

AND DCTN3 ELISA kits, Dynactin subunit 3 Proteins

Many biological assays use antibodies to detect Dynactin subunit 3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Dynactin subunit 3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Dynactin subunit 3 antibodies...

We validate the specificity of these antibodies to Dynactin subunit 3 by testing them on tissues known to express DCTN3 positively and negatively. Browse below to find the DCTN3 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DCTN3 Infographic by Boster Bio

All DCTN3 Products

Product

Figures

Specificity

Applications

Price

DCTN3 (NM_007234) Human Recombinant Protein

$1249
Cat # PROTO75935
20 µg

Anti-DCTN3 Rabbit Monoclonal Antibody

Human, Mouse, Rat

IF, IHC, ICC, WB

$370
Cat # M11728
100 μl/vial

DCTN3 (NM_007234) Human Over-expression Lysate

Human

$628
Cat # LS011258
100 µg

DCTN3 Overview

Facts about Dynactin subunit 3.

DCTN3 3D structure. Source: alphafold

Dynactin subunit 3 (DCTN3)

Together with dynein may be involved in spindle assembly and cytokinesis. .

Gene Information

Human
Gene Name:	DCTN3
Uniprot:	O75935
Entrez:	11258

Family

Belongs to:

dynactin subunit 3 family

Alternative Names

DCTN22DCTN-22; dynactin 3 (p22); dynactin 3; Dynactin complex subunit 22 kDa subunit; dynactin light chain; dynactin subunit 3; MGC111190; p22

Molecular Weight

Mass (kDA):
21.119 kDA

Genomic Context


Human

Location:	9p13.3
Sequence:	9; NC_000009.12 (34613545..34620523, complement)

Tissue Specificity

Ubiquitously expressed. Highly expressed in muscle and pancreas and detected at lower levels in brain.

Subcellular Localizations

Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Cleavage furrow. Midbody. Localizes to punctate cytoplasmic structures and to the centrosome during interphase, and to kinetochores and to spindle poles throughout mitosis. Colocalizes with dynein to the cleavage furrow and to midbody of dividing cells.

Diseases

Malignant Neoplasms
Neoplasms
Carcinoma
Malignant Neoplasm Of Prostate
Lymphatic Metastasis
Classical Galactosemia
Prostatic Neoplasms
Malignant Neoplasm Of Breast

Ductal Carcinoma
Mammary Neoplasms
Carcinogenesis

PTMs

Acetylation

Research Areas

Cell Cycle and Replication

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DCTN3

References

PMID: 9722614 by Karki S., et al. Characterization of the p22 subunit of dynactin reveals the localization of cytoplasmic dynein and dynactin to the midbody of dividing cells.