DIMT1 Antibodies

AND DIMT1 ELISA kits, DIMT1 Proteins

Many biological assays use antibodies to detect DIMT1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DIMT1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DIMT1 antibodies...

We validate the specificity of these antibodies to DIMT1 by testing them on tissues known to express DIMT1 positively and negatively. Browse below to find the DIMT1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DIMT1 Infographic by Boster Bio

All DIMT1 Products

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Specificity

Applications

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DIMT1L (DIMT1) (NM_014473) Human Recombinant Protein

1 Q&As

Coomassie blue staining of purified DIMT1 protein

$1249
Cat # PROTQ9UNQ2
20 µg

Anti-DIMT1L (DIMT1) Mouse Monoclonal Antibody [Clone ID: OTI6E7]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DIMT1L (Right lane) cDNA for 48 hrs and lysed

Western blot analysis of extracts (35ug) from 2 different cell lines by using anti-DIMT1L monoclonal antibody (1:500)

Human, Mouse, Rat

$523
Cat # M14030
100 µl

DIMT1L (DIMT1) (NM_014473) Human Over-expression Lysate

Human

$628
Cat # LS027292
20 µg, 100 µg

Anti-DIMT1 Antibody Picoband®

Western blot analysis of DIMT1 using anti-DIMT1 antibody (A14030-1)

Human, Mouse, Rat

ELISA, WB

$370
Cat # A14030-1
100 μg/vial

DIMT1 Overview

Facts about Probable dimethyladenosine transferase.

DIMT1 3D structure. Source: alphafold

Probable dimethyladenosine transferase (DIMT1)

Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle (PubMed:25851604). Involved in the pre-rRNA processing steps resulting in small-subunit rRNA production independently of its RNA-modifying catalytic activity (PubMed:25851604).

Gene Information

Human
Gene Name:	DIMT1
Uniprot:	Q9UNQ2
Entrez:	27292

Family

Belongs to:

class I-like SAM-binding methyltransferase superfamily

Alternative Names

18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase; DIM1 dimethyladenosine transferase 1-like (S. cerevisiae); DIM1 dimethyladenosine transferase 1-like; DIM1; DIMT1dimethyladenosine transferase; EC 2.1.1; EC 2.1.1.14; EC 2.1.1.183,18S rRNA dimethylase; HSA9761; HUSSY5; N'-adenosyl(rRNA) dimethyltransferase; probable dimethyladenosine transferase; S-adenosylmethionine-6-N'

Molecular Weight

Mass (kDA):
35.236 kDA

Genomic Context


Human

Location:	5q12.1
Sequence:	5; NC_000005.10 (62387254..62403905, complement)

Subcellular Localizations

Nucleus, nucleoplasm. Nucleus, nucleolus.

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DIMT1

References

PMID: 11124703 by Stanchi F., et al. Characterization of 16 novel human genes showing high similarity to yeast sequences.

PMID: 25851604 by Zorbas C., et al. The human 18S rRNA base methyltransferases DIMT1L and WBSCR22-TRMT112 but not rRNA modification are required for ribosome biogenesis.