DOCK9 Antibodies

AND DOCK9 ELISA kits, DOCK9 Proteins

Many biological assays use antibodies to detect DOCK9, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DOCK9 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DOCK9 antibodies...

We validate the specificity of these antibodies to DOCK9 by testing them on tissues known to express DOCK9 positively and negatively. Browse below to find the DOCK9 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DOCK9 Infographic by Boster Bio

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Anti-DOCK9 Antibody

Human, Mouse

ELISA, IP, IF, IHC, ICC, WB

$370
Cat # A07020
100 μl/vial

DOCK9 Overview

Facts about Dedicator of cytokinesis protein 9.

DOCK9 3D structure. Source: alphafold

Dedicator of cytokinesis protein 9 (DOCK9)

Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP. Overexpression induces filopodia formation.

Gene Information

Human
Gene Name:	DOCK9
Uniprot:	Q9BZ29
Entrez:	23348

Family

Belongs to:

DOCK family

Alternative Names

Cdc42 guanine nucleotide exchange factor zizimin-1; dedicator of cytokinesis 9; dedicator of cytokinesis protein 9; DKFZp686C11110; DKFZp686D2047; DKFZp686N04132; FLJ11949; FLJ16744; FLJ45601; KIAA1058FLJ44528; KIAA1085; ZIZ1FLJ45282; ZIZIMIN1

Molecular Weight

Mass (kDA):
236.446 kDA

Genomic Context


Human

Location:	13q32.3
Sequence:	13; NC_000013.11 (98793429..99086694, complement)

Tissue Specificity

Widely expressed, with highest expression in heart and placenta. Expressed at intermediate level in kidney, brain, lung and skeletal muscle.

Subcellular Localizations

Endomembrane system. Associated with membranes.

Diseases

Cell Invasion
Delusions
Cell Transformation, Neoplastic
Glioblastoma
Manic
Psychotic Disorders
Course Of Illness
Corneal Diseases
Leukemia

Lymphoid Leukemia
Chronic Lymphocytic Leukemia
Dysequilibrium Syndrome
Bipolar Disorder

Interacting Proteins

NEB
SMAD2
SMAD3

Pathways

Cell Migration
Phagocytosis
Cytokinesis
Cell Proliferation
Cell Motility
Dendrite Development
Cell Differentiation

Proteolysis
Localization

PTMs

Phosphorylation

Research Areas

Apoptosis
Cell Biology
Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DOCK9

References

PMID: 12172552 by Meller N., et al. Zizimin1, a novel Cdc42 activator, reveals a new GEF domain for Rho proteins.

PMID: 12432077 by Cote J.-F., et al. Identification of an evolutionarily conserved superfamily of DOCK180- related proteins with guanine nucleotide exchange activity.