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DPH5 Antibodies
AND DPH5 ELISA kits, DPH5 Proteins
Many biological assays use antibodies to detect DPH5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DPH5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DPH5 antibodies...
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DPH5 Overview
Facts about Diphthine methyl ester synthase.
Diphthine methyl ester synthase (DPH5)
S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the altered target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis.
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Gene Information
| Human | |
|---|---|
| Gene Name: | DPH5 |
| Uniprot: | Q9H2P9 |
| Entrez: | 51611 |
Family
| Belongs to: |
|---|
| diphthine synthase family |
Alternative Names
CGI-30; Diphthamide biosynthesis methyltransferase; diphthine synthase; DPH5 homolog (S. cerevisiae); EC 2.1.1.98; HSPC143; MGC61450; NPD015; protein x 0011
Molecular Weight
Mass (kDA):
31.651 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1p21.2 |
| Sequence: | 1; NC_000001.11 (100975218..101025806, complement) |
Diseases
- Diphtheria
- Neoplasms
- Polydactyly
- Radial Polydactyly
- Poisoning
Pathways
- Translation
- Methylation
- Trna Modification
- Localization
PTMs
- Amidation
Research Areas
- Lipid and Metabolism
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DPH5
bosterbio.com/bosterbio-gene-info-cards/DPH5
References
PMID: 23486472 by Wei H., et al. A modified form of diphthamide causes immunotoxin resistance in a lymphoma cell line with a deletion of the WDR85 gene.