Efhd2 Antibodies

AND Efhd2 ELISA kits, Efhd2 Proteins

Many biological assays use antibodies to detect Efhd2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Efhd2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Efhd2 antibodies...

We validate the specificity of these antibodies to Efhd2 by testing them on tissues known to express Efhd2 positively and negatively. Browse below to find the Efhd2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Efhd2 Infographic by Boster Bio

All Efhd2 Products

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Product

Figures

Specificity

Applications

Price

EFHD2 (NM_024329) Human Recombinant Protein

Coomassie blue staining of purified EFHD2 protein

$1249
Cat # PROTQ96C19
20 µg

EFHD2 (NM_024329) Human Over-expression Lysate

Human

$628
Cat # LS079180
20 µg, 100 µg

Anti-EFHD2 Antibody Picoband®

Western blot analysis of EFHD2 using anti-EFHD2 antibody (A07124-2)

IHC analysis of EFHD2 using anti-EFHD2 antibody (A07124-2)

Human, Mouse, Rat

ELISA, IP, IHC, WB

$370
Cat # A07124-2
100 μg/vial

Efhd2 Overview

Facts about EF-hand domain-containing protein D2.

EF-hand domain-containing protein D2 (Efhd2)

May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis. Plays a role as negative regulator of the canonical NF-kappa-B-activating branch.

Controls spontaneous apoptosis through the regulation of BCL2L1 abundance. .

Gene Information

Mouse
Gene Name:	Efhd2
Uniprot:	Q9D8Y0
Entrez:	27984

Family

Belongs to:

No superfamily

Alternative Names

EF hand domain containing 2; EF hand domain family, member D2; EF-hand domain family, member D2; EF-hand domain-containing protein D2; MGC4342; swiprosin 1; swiprosin-1; SWS1

Molecular Weight

Mass (kDA):
26.791 kDA

Genomic Context


Mouse

Location:	4 E1\|4 74.75 cM
Sequence:	4;

Tissue Specificity

Detected in thymus, kidney, spleen, lung, liver and brain. Highest abundance in brain and lowest in kidney and thymus.

Diseases

Anaphylaxis
Dermatitis
Nerve Degeneration
Dermatitis, Atopic
Nervous System Disorder
Malignant Paraganglionic Neoplasm
Tissue Adhesions
Mental Disorders
Cancer Patients And Suicide And Depression
Cataract

Cutaneous Anaphylaxis (disorder)
Tauopathies
Alzheimer's Disease
Tuberculosis

Pathways

Cell Adhesion
Cell Activation
Anaphylaxis
Mitosis
Immune Response
Proteolysis
Synaptic Transmission
Cellular Response To Oxidative Stress
Cell Cycle Arrest
Mast Cell Activation

Response To Oxidative Stress
Cell Cycle
Cell Death
Cell Growth
Myoblast Fusion

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Efhd2

References

PMID: 15749887 by Mielenz D., et al. Lipid rafts associate with intracellular B cell receptors and exhibit a B cell stage-specific protein composition.

PMID: 17673920 by Avramidou A., et al. The novel adaptor protein Swiprosin-1 enhances BCR signals and contributes to BCR-induced apoptosis.