- Table of Content
Also mediates monomethylation of'Lys-56' of histone H3 (H3K56me1) at G1 phase, leading to encourage interaction between histone H3 and PCNA and regulating DNA replication. Also weakly methylates 'Lys-27' of histone H3 (H3K27me).
|class V-like SAM-binding methyltransferase superfamily|
|Sequence:||6; NC_000006.12 (31879759..31897698, complement)|
Expressed in all tissues examined, with high levels in fetal liver, thymus, lymph node, spleen and peripheral blood leukocytes and lower level in bone marrow.
Nucleus. Chromosome. Associates with euchromatic regions. Does not associate with heterochromatin.
Applications: Flow Cytometry
Reactivity: Human, Mouse, Rat
Applications: ELISA, Flow Cytometry, IF, IHC-P, ICC, WB