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In embryonic stem cells, the elongin BC complex is recruited by EPOP into Polycomb group (PcG) target genes in order create genomic region that display both active and repressive chromatin properties, an important feature of pluripotent stem cells (By similarity). .
|Sequence:||8; NC_000008.11 (73945119..73972287, complement)|
Overexpressed in prostate cancer cell line PC- 3 and breast cancer cell line SK-BR-3.