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Endomucin Antibodies
AND EMCN ELISA kits, Endomucin Proteins
Many biological assays use antibodies to detect Endomucin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Endomucin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Endomucin antibodies...
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EMCN Overview
Facts about Endomucin.
Endomucin (EMCN)
Endothelial sialomucin, also called endomucin or mucin- like sialoglycoprotein, which interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix. .
Gene Information
| Human | |
|---|---|
| Gene Name: | EMCN |
| Uniprot: | Q9ULC0 |
| Entrez: | 51705 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
EMCN; EMCN2; Endomucin; MUC-14
Molecular Weight
Mass (kDA):
27.452 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 4q24 |
| Sequence: | 4; NC_000004.12 (100395341..100518052, complement) |
Tissue Specificity
Expressed in heart, kidney and lung.
Subcellular Localizations
[Isoform 1]: Cell membrane; Single-pass type I membrane protein. Membrane; Single-pass type I membrane protein. Consistently localized to the plasma membrane and less abundantly to Golgi-like perinuclear stacks.; [Isoform 2]: Secreted.
Diseases
- Tissue Adhesions
- Neoplasms
- Radiation Injury
- Leukemogenesis
- Cell Transformation, Neoplastic
- Hematologic Neoplasms
- Central Nervous System Neoplasms
- Bone Neoplasms
- Precursor T-cell Lymphoblastic Leukemia-lymphoma
- Acute Lymphocytic Leukemia
- Central Nervous System Lymphoma
- Osteosarcoma
- Arthritis
Pathways
- Cell Adhesion
- Pathogenesis
- Tube Formation
- Glycosylation
- Cell Growth
- Localization
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EMCN
bosterbio.com/bosterbio-gene-info-cards/EMCN
References
PMID: 11418125 by Kinoshita M., et al. Identification of human endomucin-1 and -2 as membrane-bound O- sialoglycoproteins with anti-adhesive activity.
PMID: 12485444 by Kuhn A., et al. Expression of endomucin, a novel endothelial sialomucin, in normal and diseased human skin.