EML2 Antibodies

AND EML2 ELISA kits, EML2 Proteins

Many biological assays use antibodies to detect EML2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with EML2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop EML2 antibodies...

We validate the specificity of these antibodies to EML2 by testing them on tissues known to express EML2 positively and negatively. Browse below to find the EML2 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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EML2 Infographic by Boster Bio

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EML2 Overview

Facts about Echinoderm microtubule-associated protein-like 2.

EML2 3D structure. Source: alphafold

Echinoderm microtubule-associated protein-like 2 (EML2)

Tubulin binding protein that inhibits microtubule nucleation and growth, leading to shorter microtubules. .

Gene Information

Human
Gene Name:	EML2
Uniprot:	O95834
Entrez:	24139

Family

Belongs to:

WD repeat EMAP family

Alternative Names

echinoderm microtubule associated protein like 2; echinoderm microtubule-associated protein-like 2; echinoderm MT-associaated protein (EMAP)-like protein 70; echinoderm MT-associated protein (EMAP)-like protein 70; ELP70; EMAP-2huEMAP-2; EMAP2microtubule-associated protein like echinoderm EMAP; EMAPL2; HuEMAP-2; TRTLT2

Molecular Weight

Mass (kDA):
70.679 kDA

Genomic Context


Human

Location:	19q13.32
Sequence:	19; NC_000019.10 (45609396..45645629, complement)

Tissue Specificity

Ubiquitous.

Subcellular Localizations

Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Colocalizes with the microtubule cytoskeleton. Colocalizes with the mitotic spindle.

Diseases

Cell Transformation, Neoplastic
Adenoma
Complete Hearing Loss
Deafness Congenital
Traumatic Brain Injury
Retinitis Pigmentosa
Usher Syndrome, Type I
Usher Syndrome
Neoplasms

Pituitary Adenoma
Pituitary Diseases
Vestibular Diseases
Brain Injuries

Interacting Proteins

EXD1
REL

Pathways

Methylation
Mrna Splicing
Cell Proliferation
Dna Methylation
Pre-mirna Processing
Localization

PTMs

Cleavage

Methylation

Research Areas

Vision

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EML2

References

PMID: 10521658 by Lepley D.M., et al. Sequence and expression patterns of a human EMAP-related protein-2 (HuEMAP-2).

PMID: 11694528 by Eichenmuller B., et al. The human EMAP-like protein-70 (ELP70) is a microtubule destabilizer that localizes to the mitotic apparatus.