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Eosinophil peroxidase Antibodies

AND EPX ELISA kits, Eosinophil peroxidase Proteins

Many biological assays use antibodies to detect Eosinophil peroxidase, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Eosinophil peroxidase in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Eosinophil peroxidase antibodies...

We validate the specificity of these antibodies to Eosinophil peroxidase by testing them on tissues known to express EPX positively and negatively. Browse below to find the EPX antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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EPX Infographic by Boster Bio

EPX protein infographic

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Anti-Eosinophil peroxidase EPX Antibody

Western blot (WB) analysis of EPX polyclonal antibody at 1:500 dilution
Lane1:HEK293T whole cell lysate
Lane2:sp2/0 whole cell lysate
Lane3:PC12 whole cell lysate

Western blot (WB) analysis of EPX polyclonal antibody at 1:500 dilution
Lane1:HEK293T whole cell lysate
Lane2:sp2/0 whole cell lysate
Lane3:PC12 whole cell lysate

Human, Mouse, Rat

WB

$405
Cat # A05098
100ul

EPX Overview

Facts about Eosinophil peroxidase.

EPX 3D structure

EPX 3D structure. Source: alphafold

Eosinophil peroxidase (EPX)

Mediates tyrosine nitration of secondary granule proteins in older resting eosinophils. Shows significant inhibitory activity towards Mycobacterium tuberculosis H37Rv by inducing bacterial fragmentation and lysis.

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Gene Information

Human
Gene Name:	EPX
Uniprot:	P11678
Entrez:	8288

Gene Information

Family

Belongs to:

peroxidase family

Family

Alternative Names

EC 1.11.1.7; eosinophil peroxidase; EPOEPER; EPPEC 1.11.1; EPX-PEN

Molecular Weight

Mass (kDA):
81.04 kDA

Molecular Weight

Genomic Context


Human

Location:	17q22
Sequence:	17; NC_000017.11 (58192726..58205174)

Subcellular Localizations

Cytoplasmic granule. Cytoplasmic granules of eosinophils.

Subcellular Localization

Diseases

Asthma
Inflammation
Allergy
Dermatitis, Atopic
Eosinophilia
Bronchial Hyperreactivity
Dermatitis
Ulcer
Childhood Asthma
Colitis
Inflammatory Bowel Diseases
Ulcerative Colitis
Intestinal Diseases

Rhinorrhea
Malignant Neoplasms
Food Allergy
Allergic Asthma
Immediate Hypersensitivity
Hay Fever
Infective Disorder

Disease

Pathways

Eosinophil Activation
Excretion
Eosinophil Degranulation
Pathogenesis
Secretion
Sensitization
Cell Activation
Hypersensitivity
Anaphylaxis
Mast Cell Activation
Neutrophil Degranulation
Coagulation
Cell Growth

Cell Adhesion
Cell Proliferation
Circadian Rhythm
T Cell Activation
Glycosylation
Localization
Inflammatory Response

Pathways

PTMs

Reduction
Glycosylation

Cleavage
Oxidation

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EPX

References

PMID: 2550461 by Sakamaki K., et al. Molecular cloning and characterization of a chromosomal gene for human eosinophil peroxidase.

PMID: 2541222 by Ten R.M., et al. Molecular cloning of the human eosinophil peroxidase. Evidence for the existence of a peroxidase multigene family.