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Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can lead to cytokinesis failure. Also required for homology-directed fix (HDR) of DNA double-strand breaks, in combination with SLX4.
|Sequence:||19; NC_000019.10 (45407334..45451547, complement)|
[Isoform 1]: Nucleus.; [Isoform 2]: Cytoplasm. Nucleus.; [Isoform 3]: Nucleus.; [Isoform 4]: Nucleus.