Eif2s3x Antibodies

AND Eif2s3x ELISA kits, Eif2s3x Proteins

Many biological assays use antibodies to detect Eif2s3x, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Eif2s3x in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Eif2s3x antibodies...

We validate the specificity of these antibodies to Eif2s3x by testing them on tissues known to express Eif2s3x positively and negatively. Browse below to find the Eif2s3x antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Eif2s3x Infographic by Boster Bio

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Eif2s3x Overview

Facts about Eukaryotic translation initiation factor 2 subunit 3, X-linked.

Eif2s3x 3D structure. Source: alphafold

Eukaryotic translation initiation factor 2 subunit 3, X-linked (Eif2s3x)

As a subunit of eukaryotic initiation factor 2 (eIF2), involved in the early steps of protein synthesis. In the presence of GTP, eIF2 forms a ternary complex with initiator tRNA Met-tRNAi and then recruits the 40S ribosomal complex, a measure that determines the speed of protein translation.

This step is followed by mRNA binding to form the 43S pre-initiation complicated. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF2 and launch of an eIF2-GDP binary complex.

Gene Information

Mouse
Gene Name:	Eif2s3x
Uniprot:	Q9Z0N1
Entrez:	26905

Family

Belongs to:

TRAFAC class translation factor GTPase superfamily

Alternative Names

Eukaryotic translation initiation factor 2 subunit 3, X-linked

Molecular Weight

Mass (kDA):
51.065 kDA

Genomic Context


Mouse

Location:	X C3\|X 41.52 cM
Sequence:	X;

Tissue Specificity

Widely expressed. In the brain, high mRNA levels are observed in specific regions, including the habenula, anterodorsal thalamic nucleus, hippocampus, hypothalamus, and cerebellum. Also expressed in the embryonic brain. There is a differential expression between males and females, wich is tissue- specific. Females tend to have higher expression levels than males in the brain (cortex, hippocampus and paraventricular nucleus, but not in the habenula), as well as in other tissues. The up- regulation observed in females at the mRNA level may be due to the presence of 2 active copies of the gene.

PTMs

Acetylation

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Eif2s3x

References

PMID: 9736774 by Ehrmann I.E., et al. Characterization of genes encoding translation initiation factor eIF- 2gamma in mouse and human: sex chromosome localization, escape from X- inactivation and evolution.

PMID: 12023983 by Xu J., et al. Sex differences in sex chromosome gene expression in mouse brain.