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Not included in DNA double-strand breaks resection (PubMed:20603015, PubMed:20603016). Referred to as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at each third nucleotide, allowing to excise an ICL from 1 strand through flanking incisions.
|Sequence:||15; NC_000015.10 (30903852..30943108)|
Nucleus. Localizes at sites of DNA damage following recruitment by monoubiquitinated FANCD2 (PubMed:20603015, PubMed:20603016). Localizes to stalled replication forks via its UBZ4-type zinc finger (PubMed:20935496).