FBXL21P Antibodies

AND FBXL21P ELISA kits, FBXL21P Proteins

Many biological assays use antibodies to detect FBXL21P, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FBXL21P in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FBXL21P antibodies...

We validate the specificity of these antibodies to FBXL21P by testing them on tissues known to express FBXL21P positively and negatively. Browse below to find the FBXL21P antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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FBXL21P Infographic by Boster Bio

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FBXL21P Overview

Facts about Putative F-box/LRR-repeat protein 21.

FBXL21P 3D structure. Source: alphafold

Putative F-box/LRR-repeat protein 21 (FBXL21P)

Substrate-recognition component of the SCF(FBXL21) E3 ubiquitin ligase complex involved in circadian rhythm function. Plays a key role in the maintenance of both the speed and the robustness of the circadian clock oscillation.

The SCF(FBXL21) complex chiefly acts in the cytosol and mediates ubiquitination of CRY proteins (CRY1 and CRY2), leading to CRY proteins stabilization. The SCF(FBXL21) complex counteracts the activity of the SCF(FBXL3) complex and shields CRY proteins from degradation.

Gene Information

Human
Gene Name:	FBXL21P
Uniprot:	Q9UKT6
Entrez:	26223

Family

Belongs to:

No superfamily

Alternative Names

Putative F-box/LRR-repeat protein 21

Molecular Weight

Mass (kDA):
49.152 kDA

Genomic Context


Human

Location:	5q31.1
Sequence:	5; NC_000005.10 (135930297..135941996)

Subcellular Localizations

Cytoplasm, cytosol. Nucleus. Mainly localizes in the cytosol. Present at low level in the nucleus (By similarity).

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FBXL21P

References

PMID: 10531035 by Cenciarelli C., et al. Identification of a family of human F-box proteins.