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- Table of Contents
Facts about F-BAR domain only protein 1.
May regulate Bmp signaling by regulating clathrin-mediated endocytosis of Bmp receptors. .
Human | |
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Gene Name: | FCHO1 |
Uniprot: | O14526 |
Entrez: | 23149 |
Belongs to: |
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FCHO family |
FCH domain only 1; FCH domain only protein 1; KIAA0290
Mass (kDA):
96.861 kDA
Human | |
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Location: | 19p13.11 |
Sequence: | 19; NC_000019.10 (17747718..17788562) |
Membrane, clathrin-coated pit; Peripheral membrane protein; Cytoplasmic side. Associated with forming but not mature clathrin-coated vesicles. The recruitment to coated-pits precede the one of clathrin and the adaptor protein complex AP-2. According to PubMed:17617719 it may also dynamically associate with Golgi/TGN membranes.
PMID: 9179496 by Ohara O., et al. Construction and characterization of human brain cDNA libraries suitable for analysis of cDNA clones encoding relatively large proteins.
PMID: 17617719 by Sakaushi S., et al. Dynamic behavior of FCHO1 revealed by live-cell imaging microscopy: its possible involvement in clathrin-coated vesicle formation.