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- Table of Contents
Facts about Filamin A-interacting protein 1-like.
Inhibits melanoma development When expressed in tumor- associated vasculature. .
| Human | |
|---|---|
| Gene Name: | FILIP1L |
| Uniprot: | Q4L180 |
| Entrez: | 11259 |

| Belongs to: |
|---|
| FILIP1 family |

90 kDa GPBP-interacting protein; downregulated in ovarian cancer 1 81 kDa isoform; filamin A interacting protein 1-like; GIP130a; GIP130b; GIP130c
Mass (kDA):
130.382 kDA

| Human | |
|---|---|
| Location: | 3q12.1 |
| Sequence: | 3; NC_000003.12 (99833144..100114513, complement) |
Expressed in endothelial cells, colon and colon cancers. In the colon, expressed in the vasculature and muscularis mucosa. In colon cancer, strongly expressed in tumor stroma and the vasculature (at protein level). Expressed in ovarian epithelial cells. Down-regulated in ovarian cancer.
Cytoplasm. Membrane. Nucleus.




PMID: 8314147 by Mok S.C., et al. Molecular cloning of differentially expressed genes in human epithelial ovarian cancer.
PMID: 15935955 by Tandle A.T., et al. Endothelial monocyte activating polypeptide-II induced gene expression changes in endothelial cells.