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FRAT2 Antibodies

AND FRAT2 ELISA kits, FRAT2 Proteins

Many biological assays use antibodies to detect FRAT2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FRAT2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FRAT2 antibodies...

We validate the specificity of these antibodies to FRAT2 by testing them on tissues known to express FRAT2 positively and negatively. Browse below to find the FRAT2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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FRAT2 Infographic by Boster Bio

FRAT2 protein infographic

All FRAT2 Products

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FRAT2 (NM_012083) Human Over-expression Lysate

FRAT2 Human Over-expression Lysates NM_012083

FRAT2 Human Over-expression Lysates NM_012083

Human

$628
Cat # LS023401
20 µg, 100 µg

FRAT2 Overview

Facts about GSK-3-binding protein FRAT2.

FRAT2 3D structure

FRAT2 3D structure. Source: alphafold

GSK-3-binding protein FRAT2 (FRAT2)

Positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3. .

Gene Information

Human
Gene Name:	FRAT2
Uniprot:	O75474
Entrez:	23401

Gene Information

Family

Belongs to:

GSK-3-binding protein family

Family

Alternative Names

FRAT2; frequently rearranged in advanced T-cell lymphomas 2FRAT-2; GSK-3 binding protein FRAT2; GSK-3-binding protein FRAT2; MGC10562

Molecular Weight

Mass (kDA):
24.051 kDA

Molecular Weight

Genomic Context


Human

Location:	10q24.1
Sequence:	10; NC_000010.11 (97332497..97334729, complement)

Diseases

Malignant Neoplasms
Neoplasms
Carcinogenesis
Malignant Neoplasm Of Stomach
Leukemia
Embryonal Carcinoma
Malignant Tumor Of Cervix
Carcinoma
Myeloid Leukemia
T-cell Lymphoma
Stomach Neoplasms
Malignant Neoplasm Of Breast
Myeloid Leukemia, Chronic

Lymphoma
Malignant Neoplasm Of Pancreas
Cell Transformation, Neoplastic
Malignant Paraganglionic Neoplasm
Growth Retardation
Germ Cell Tumor
Neoplasm Metastasis

Disease

Pathways

Cell Growth
Cell Adhesion
Dna Hypomethylation
Dna Methylation
Dna Demethylation
Nuclear Export
Localization
Demethylation
Methylation
Regeneration
Tissue Regeneration

Cell Differentiation
Establishment Of Tissue Polarity
Rna Interference
Tissue Homeostasis
Nuclear Import

Pathways

PTMs

Phosphorylation

Methylation

Demethylation

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FRAT2

References

PMID: 11237732 by Saitoh T., et al. Molecular cloning and characterization of FRAT2, encoding a positive regulator of the WNT signaling pathway.

PMID: 9635432 by Yost C., et al. GBP, an inhibitor of GSK-3, is implicated in Xenopus development and oncogenesis.