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- Table of Contents
FTCD Antibodies
AND FTCD ELISA kits, FTCD Proteins
Many biological assays use antibodies to detect FTCD, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FTCD in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FTCD antibodies...
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FTCD Infographic by Boster Bio
All FTCD Products
Product
Figures
Specificity
Applications
Price
Human
Flow Cytometry, IHC, WB
$370
Cat # M05499
100 μl
Cat # M05499
100 μl
Human, Monkey, Mouse
WB
$523
Cat # M05499-3
100 µl
Cat # M05499-3
100 µl
Human, Monkey
Flow Cytometry, WB
$523
Cat # M05499-1
100 µl
Cat # M05499-1
100 µl
Human, Mouse, Rat
ELISA, IF, IHC, ICC, WB
$370
Cat # A05499-2
100 μg/vial
Cat # A05499-2
100 μg/vial
FTCD Overview
Facts about Formimidoyltransferase-cyclodeaminase.
Formimidoyltransferase-cyclodeaminase (FTCD)
Folate-dependent receptor, which shows both transferase and deaminase activity. Serves to station one-carbon units from formiminoglutamate into the folate pool.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | FTCD |
| Uniprot: | O95954 |
| Entrez: | 10841 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
formimidoyltransferase cyclodeaminase; formimidoyltransferase-cyclodeaminase; formiminotransferase cyclodeaminase; Formiminotransferase-cyclodeaminase; human formiminotransferase cyclodeaminase, EC 4.3.1.410formiminotransferase-cyclodeaminase; LCHC1
Molecular Weight
Mass (kDA):
58.927 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 21q22.3 |
| Sequence: | 21; NC_000021.9 (46135981..46156482, complement) |
Subcellular Localizations
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Golgi apparatus. More abundantly located around the mother centriole.
Diseases
- Hepatitis
- Hepatitis, Autoimmune
- Autoimmune Reaction
- Glutamate Formiminotransferase Deficiency
- Malignant Neoplasms
- Neoplasms
- Liver Carcinoma
- Inflammation
- Burkitt Lymphoma
- Carcinoma
- Injury To Liver
- 5,10-methylenetetrahydrofolate Reductase Deficiency
Interacting Proteins
- CCDC155
- MED4
Pathways
- Pathogenesis
- Localization
- Transport
- Secretory Pathway
- Dna Methylation
- Methylation
- Cell Cycle
- Golgi Localization
- Proteolysis
- Gluconeogenesis
- Protein Secretion
- Protein Transport
- Nuclear Export
PTMs
- Methylation
Research Areas
- Cellular Markers
- Golgi Apparatus Markers
- Lipid and Metabolism
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FTCD
bosterbio.com/bosterbio-gene-info-cards/FTCD
References
PMID: 10773664 by Solans A., et al. Cloning and characterization of human FTCD on 21q22.3, a candidate gene for glutamate formiminotransferase deficiency.
PMID: 10029623 by Lapierre P., et al. Formiminotransferase cyclodeaminase is an organ-specific autoantigen recognized by sera of patients with autoimmune hepatitis.