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GADD45B Antibodies
AND GADD45B ELISA kits, GADD45B Proteins
Many biological assays use antibodies to detect GADD45B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GADD45B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GADD45B antibodies...
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GADD45B Overview
Facts about Growth arrest and DNA damage-inducible protein GADD45 beta.
Growth arrest and DNA damage-inducible protein GADD45 beta (GADD45B)
Involved in the regulation of growth and apoptosis. Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | GADD45B |
| Uniprot: | O75293 |
| Entrez: | 4616 |
Family
| Belongs to: |
|---|
| GADD45 family |
Alternative Names
DKFZp566B133; GADD45BETA; growth arrest and DNA damage-inducible protein GADD45 beta; growth arrest and DNA-damage-inducible, beta; MYD118DKFZP566B133; Myeloid differentiation primary response protein MyD118; Negative growth regulatory protein MyD118
Molecular Weight
Mass (kDA):
17.818 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 19p13.3 |
| Sequence: | 19; NC_000019.10 (2476127..2478259) |
Diseases
- Growth Arrest
- Malignant Neoplasms
- Neoplasms
- Carcinoma
- Inflammation
- Cell Transformation, Neoplastic
- Liver Carcinoma
- Liver Neoplasms
- Malignant Neoplasm Of Lung
- Leukemia
- Genotoxic Stress
- Malignant Neoplasm Of Breast
- Degenerative Polyarthritis
Interacting Proteins
- MAP2K7
- MAP3K4
Pathways
- Cell Cycle
- Cell Death
- Cell Growth
- Dna Repair
- Cell Cycle Arrest
- Programmed Cell Death
- Cell Proliferation
- Demethylation
- Dna Demethylation
- Immune Response
- Methylation
- Cell Differentiation
- Dna Replication
PTMs
- Phosphorylation
- Demethylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GADD45B
bosterbio.com/bosterbio-gene-info-cards/GADD45B
References
PMID: 9827804 by Takekawa M., et al. A family of stress-inducible GADD45-like proteins mediate activation of the stress-responsive MTK1/MEKK4 MAPKKK.
PMID: 10773677 by Gong R., et al. Assignment of human GADD45G to chromosome 9q22.1-->q22.3 by radiation hybrid mapping.