Galanin receptor type 2 Antibodies

AND GALR2 ELISA kits, Galanin receptor type 2 Proteins

Many biological assays use antibodies to detect Galanin receptor type 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Galanin receptor type 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Galanin receptor type 2 antibodies...

We validate the specificity of these antibodies to Galanin receptor type 2 by testing them on tissues known to express GALR2 positively and negatively. Browse below to find the GALR2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GALR2 Infographic by Boster Bio

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Anti-Galanin receptor type 2 GALR2 Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A04084
100ul

GALR2 Overview

Facts about Galanin receptor type 2.

GALR2 3D structure. Source: alphafold

Galanin receptor type 2 (GALR2)

Receptor for the hormone galanin and GALP.
Receptor for the hormone spexin-1 (PubMed:24517231).

The activity of this receptor is mediated by G proteins that activate the phospholipase C/protein kinase C pathway (via G(q)) and that inhibit adenylyl cyclase (via G(I)). .

Gene Information

Human
Gene Name:	GALR2
Uniprot:	O43603
Entrez:	8811

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

GAL2R; GAL2-R; Galanin R2; galanin receptor 2; galanin receptor type 2; GalaninR2; GALNR2; GALNR2MGC125984; GALR2; GALR-2; MGC125983

Molecular Weight

Mass (kDA):
41.7 kDA

Genomic Context


Human

Location:	17q25.1
Sequence:	17; NC_000017.11 (76070824..76077537)

Tissue Specificity

Expressed abundantly within the central nervous system in both hypothalamus and hippocampus. In peripheral tissues, the strongest expression was observed in heart, kidney, liver, and small intestine.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Nervousness
Pain
Depressive Disorder
Neoplasms
Pituitary Diseases
Nerve Damage
Alzheimer's Disease
Anxiety Disorders
Epilepsy
Malignant Neoplasms
Neuralgia
Pertussis

Status Epilepticus
Obesity
Carcinoma
Peripheral Nerve Injuries
Mood Disorders
Malignant Squamous Cell Neoplasm
Major Depressive Disorder

Interacting Proteins

Pathways

Localization
Secretion
Cell Proliferation
Feeding Behavior
Cognition
Neurogenesis
Regeneration
Cell Death
Methylation
Reverse Transcription
Energy Homeostasis
Transport
Cell Cycle Arrest

Cell Cycle
Hormone Secretion
Lactation
Membrane Hyperpolarization
Neuroprotection
Cellular Localization
Innervation

PTMs

Phosphorylation
Methylation

Cleavage
Demethylation

Amidation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GALR2

References

PMID: 9480833 by Bloomquist B.T., et al. Cloning and expression of the human galanin receptor GalR2.

PMID: 9880084 by Borowsky B., et al. Cloning and characterization of the human galanin GALR2 receptor.