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- Table of Contents
Facts about Chorion-specific transcription factor GCMa.
Binds to the SYDE1 promoter (PubMed:27917469). Has a central role in mediating the differentiation of trophoblast cells together both the villous and extravillous pathways in placental development (PubMed:19219068).
Human | |
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Gene Name: | GCM1 |
Uniprot: | Q9NP62 |
Entrez: | 8521 |
Belongs to: |
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No superfamily |
GCM motif protein 1; GCMA; glial cells missing (Drosophila) homolog a; glial cells missing homolog 1 (Drosophila); Glial cells missing homolog 1; hGCMachorion-specific transcription factor GCMa
Mass (kDA):
49.268 kDA
Human | |
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Location: | 6p12.1 |
Sequence: | 6; NC_000006.12 (53126961..53262803, complement) |
Higly expressed in the placenta (PubMed:10542267). Expressed in trophoblast cells of the villi (PubMed:27917469).
Nucleus.
PMID: 8962155 by Akiyama Y., et al. The gcm-motif: a novel DNA binding motif conserved in Drosophila and mammals.
PMID: 10542267 by Yamada K., et al. A GCM motif protein is involved in placenta-specific expression of human aromatase gene.