GCNT4 Antibodies

AND GCNT4 ELISA kits, GCNT4 Proteins

Many biological assays use antibodies to detect GCNT4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GCNT4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GCNT4 antibodies...

We validate the specificity of these antibodies to GCNT4 by testing them on tissues known to express GCNT4 positively and negatively. Browse below to find the GCNT4 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GCNT4 Infographic by Boster Bio

All GCNT4 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-GCNT4 Antibody

Human, Mouse

ELISA, WB

$380
Cat # A16200
100ul

C2GNT3 (GCNT4) (NM_016591) Human Over-expression Lysate

Human

$960
Cat # LS051301
20 µg, 100 µg

GCNT4 Overview

Facts about Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4.

GCNT4 3D structure. Source: alphafold

Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4 (GCNT4)

Glycosyltransferase that mediates core 2 O-glycan branching, an important step in mucin-type biosynthesis. Does not have core 4 O-glycan or I-branching enzyme activity.

Gene Information

Human
Gene Name:	GCNT4
Uniprot:	Q9P109
Entrez:	51301

Family

Belongs to:

glycosyltransferase 14 family

Alternative Names

beta-1,3-galactosyl-O-glycosyl-glycoproteinbeta-1,6-N-acetylglucosaminyltransferase 4; C2GNT3; core 2 beta-1,6-N-acetylglucosaminyltransferase 3; Core 2-branching enzyme 3; Core2-GlcNAc-transferase 3; EC 2.4.1.102; GCNT4; glucosaminyl (N-acetyl) transferase 4, core 2; glucosaminyl (N-acetyl) transferase 4, core 2(beta-1,6-N-acetylglucosaminyltransferase); Gm279; Gm73

Molecular Weight

Mass (kDA):
53.052 kDA

Genomic Context


Human

Location:	5q13.3
Sequence:	5; NC_000005.10 (75025346..75052558, complement)

Tissue Specificity

Predominantly expressed in thymus. Weakly expressed in pancreas, peripheral blood leukocytes, placenta, small intestine and stomach. Barely detectable in liver, spleen, lung and lymph node.

Subcellular Localizations

Golgi apparatus membrane; Single-pass type II membrane protein.

Diseases

Nematode Infections
Hyperplasia
Trematode Infections

Pathways

Fucosylation

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GCNT4

References

PMID: 10753916 by Schwientek T., et al. Control of O-glycan branch formation. Molecular cloning and characterization of a novel thymus-associated core 2 beta1, 6-n- acetylglucosaminyltransferase.