Gem-associated protein 5 Antibodies

AND GEMIN5 ELISA kits, Gem-associated protein 5 Proteins

Many biological assays use antibodies to detect Gem-associated protein 5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Gem-associated protein 5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Gem-associated protein 5 antibodies...

We validate the specificity of these antibodies to Gem-associated protein 5 by testing them on tissues known to express GEMIN5 positively and negatively. Browse below to find the GEMIN5 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GEMIN5 Infographic by Boster Bio

All GEMIN5 Products

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Gemin 5 (GEMIN5) (NM_015465) Human Over-expression Lysate

Human

$960
Cat # LS025929
20 µg, 100 µg

Anti-GEMIN5 Antibody

Human, Mouse

ELISA, IP, IF, IHC, ICC, WB

$370
Cat # A06458
100 μl/vial

GEMIN5 Overview

Facts about Gem-associated protein 5.

GEMIN5 3D structure. Source: alphafold

Gem-associated protein 5 (GEMIN5)

Required for the assembly of the SMN complex that plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (PubMed:16857593, PubMed:18984161, PubMed:20513430). Thereby, plays an important role in the splicing of cellular pre- mRNAs.

Most spliceosomal snRNPs have a standard set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complicated by the chaperone CLNS1A that controls the assembly of the core snRNP (PubMed:18984161).

Gene Information

Human
Gene Name:	GEMIN5
Uniprot:	Q8TEQ6
Entrez:	25929

Family

Belongs to:

WD repeat gemin-5 family

Alternative Names

DKFZp586M1824; EC 2.7.7.8; EC 5.4.2.1; gem (nuclear organelle) associated protein 5; gem-associated protein 5; gemin 5; Gemin5; MGC142174

Molecular Weight

Mass (kDA):
168.589 kDA

Genomic Context


Human

Location:	5q33.2
Sequence:	5; NC_000005.10 (154887411..154938216, complement)

Subcellular Localizations

Nucleus, nucleoplasm. Nucleus, gem. Cytoplasm. Found both in the nucleoplasm and in nuclear bodies called gems (Gemini of Cajal bodies) that are often in proximity to Cajal (coiled) bodies. Also found in the cytoplasm.