GLRA2 Antibodies

AND GLRA2 ELISA kits, GLRA2 Proteins

Many biological assays use antibodies to detect GLRA2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GLRA2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GLRA2 antibodies...

We validate the specificity of these antibodies to GLRA2 by testing them on tissues known to express GLRA2 positively and negatively. Browse below to find the GLRA2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GLRA2 Infographic by Boster Bio

All GLRA2 Products

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alpha 2 Glycine Receptor (GLRA2) (NM_002063) Human Over-expression Lysate

alpha 2 Glycine Receptor (GLRA2) Human Over-expression Lysates NM_001118885

Human

$628
Cat # LS002742
20 µg, 100 µg

Anti-GLRA2 Antibody Picoband®

Western blot analysis of GLRA2 using anti-GLRA2 antibody (A06620-1)

Human, Mouse, Rat

ELISA, WB

$370
Cat # A06620-1
100 μg/vial

GLRA2 Overview

Facts about Glycine receptor subunit alpha-2.

GLRA2 3D structure. Source: alphafold

Glycine receptor subunit alpha-2 (GLRA2)

Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine (PubMed:2155780, PubMed:15302677, PubMed:16144831, PubMed:23895467, PubMed:25445488).

Channel opening can be triggered by taurine and beta-alanine (PubMed:15302677). Plays a role in the down-regulation of neuronal excitability.

Gene Information

Human
Gene Name:	GLRA2
Uniprot:	P23416
Entrez:	2742

Family

Belongs to:

ligand-gated ion channel (TC 1.A.9) family

Alternative Names

Glycine receptor subunit alpha-2

Molecular Weight

Mass (kDA):
52.002 kDA

Genomic Context


Human

Location:	Xp22.2
Sequence:	X; NC_000023.11 (14529298..14731812)

Subcellular Localizations

Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell junction, synapse. Cell membrane; Multi-pass membrane protein. Cell projection.

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GLRA2

References

PMID: 2155780 by Grenningloh G., et al. Alpha subunit variants of the human glycine receptor: primary structures, functional expression and chromosomal localization of the corresponding genes.

PMID: 9674912 by Cummings C.J., et al. Analysis of the genomic structure of the human glycine receptor alpha-2 subunit gene and exclusion of this gene as a candidate for Rett syndrome.