GMPS Antibodies

AND GMPS ELISA kits, GMPS Proteins

Many biological assays use antibodies to detect GMPS, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GMPS in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GMPS antibodies...

We validate the specificity of these antibodies to GMPS by testing them on tissues known to express GMPS positively and negatively. Browse below to find the GMPS antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for GMPS? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the GMPS Western Blot Guide

GMPS Infographic by Boster Bio

All GMPS Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-GMPS Antibody Picoband®

Western blot analysis of GMPS using anti-GMPS antibody (A03643-1)

Flow Cytometry analysis of HELA cells using anti-GMPS antibody (A03643-1)

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A03643-1
100 μg/vial

Anti-Zebrafish GMPS Antibody

IHC analysis of GMPS using anti-GMPS antibody (AZB8JLW8)

Zebrafish

IHC

$470
Cat # AZB8JLW8
100 μg/vial

GMP Synthase (GMPS) (NM_003875) Human Over-expression Lysate

Human

$628
Cat # LS008833
20 µg, 100 µg

GMP Synthase (GMPS) (NM_003875) Human Recombinant Protein

Coomassie blue staining of purified GMPS protein

$1249
Cat # PROTP49915
20 µg

GMPS Overview

Facts about GMP synthase [glutamine-hydrolyzing].

GMPS 3D structure. Source: alphafold

GMP synthase [glutamine-hydrolyzing] (GMPS)

Involved in the de novo synthesis of guanine nucleotides that aren't just essential for DNA and RNA synthesis, but also offer GTP, which is involved in many of cellular processes important for cell division. .

Gene Information

Human
Gene Name:	GMPS
Uniprot:	P49915
Entrez:	8833

Family

Belongs to:

No superfamily

Alternative Names

EC 6.3.5.2; Glutamine amidotransferase; GMP synthase [glutamine-hydrolyzing]; GMP synthase; GMP synthetase; guanine monphosphate synthetase; guanosine 5'-monophosphate synthase; MLL/GMPS fusion protein

Molecular Weight

Mass (kDA):
76.715 kDA

Genomic Context


Human

Location:	3q25.31
Sequence:	3; NC_000003.12 (155869430..155944020)

Subcellular Localizations

Cytoplasm.

Diseases

Ventricular Dysfunction, Left
Heart Failure
Pathologic Vasoconstriction
Observation Of Neuromuscular Block
Malignant Neoplasms
Neoplasms
Ischemia
Myocardial Ischemia
Steroid Sulfatase Deficiency Disease
Cicatrix
Atherosclerosis

Neoplasm Metastasis
Neoplasms, Second Primary
Malignant Neoplasm Of Breast
Inflammatory Bowel Diseases
Intestinal Diseases
Rheumatism

Pathways

Vasoconstriction
Protein Phosphorylation
Vascular Smooth Muscle Contraction
Smooth Muscle Contraction
Immune Response
Muscle Contraction
Histone Modification
Localization
Dna Replication
Cellular Localization

Cell Cycle
S Phase
Pathogenesis
Innervation

PTMs

Phosphorylation

Cleavage

Amination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GMPS

References

PMID: 8089153 by Hirst M., et al. Human GMP synthetase. Protein purification, cloning, and functional expression of cDNA.

PMID: 11110714 by Pegram L.D., et al. t(3;11) translocation in treatment-related acute myeloid leukemia fuses MLL with the GMPS (guanosine 5-prime monophosphate synthetase) gene.