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GNAT2 Antibodies
AND GNAT2 ELISA kits, GNAT2 Proteins
Many biological assays use antibodies to detect GNAT2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GNAT2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GNAT2 antibodies...
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GNAT2 Infographic by Boster Bio
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GNAT2 Overview
Facts about Guanine nucleotide-binding protein G(t) subunit alpha-2.
Guanine nucleotide-binding protein G(t) subunit alpha-2 (GNAT2)
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Transducin is an amplifier and one of the transducers of a visual impulse that performs the coupling between rhodopsin and cGMP-phosphodiesterase.
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Gene Information
| Human | |
|---|---|
| Gene Name: | GNAT2 |
| Uniprot: | P19087 |
| Entrez: | 2780 |
Family
| Belongs to: |
|---|
| G-alpha family |
Alternative Names
Guanine nucleotide-binding protein G(t) subunit alpha-2
Molecular Weight
Mass (kDA):
40.176 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1p13.3 |
| Sequence: | 1; NC_000001.11 (109603091..109619538, complement) |
Tissue Specificity
Retinal rod outer segment.
Subcellular Localizations
Cell projection, cilium, photoreceptor outer segment. Photoreceptor inner segment. Localizes mainly in the outer segment in the dark-adapted state, whereas is translocated to the inner part of the photoreceptors in the light-adapted state. During dark-adapted conditions, in the presence of UNC119 mislocalizes from the outer segment to the inner part of rod photoreceptors which leads to decreased photoreceptor damage caused by light.
Diseases
- Achromatopsia 4 (ACHM4)
PTMs
- ADP-ribosylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GNAT2
bosterbio.com/bosterbio-gene-info-cards/GNAT2
References
PMID: 2534964 by Lerea C.L., et al. Alpha transducin is present in blue-, green-, and red-sensitive cone photoreceptors in the human retina.
PMID: 1936270 by Kubo M., et al. Molecular cloning and sequence analysis of cDNA and genomic DNA for the human cone transducin alpha subunit.