GPX5 Antibodies

AND GPX5 ELISA kits, GPX5 Proteins

Many biological assays use antibodies to detect GPX5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GPX5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GPX5 antibodies...

We validate the specificity of these antibodies to GPX5 by testing them on tissues known to express GPX5 positively and negatively. Browse below to find the GPX5 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GPX5 Infographic by Boster Bio

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Anti-GPX5 Antibody Picoband®

2 Citations

Western blot analysis of GPX5 using anti-GPX5 antibody (A10324-1)

IHC analysis of GPX5 using anti-GPX5 antibody (A10324-1)

Human, Mouse, Rat

ELISA, IF, IHC, ICC, WB

$370
Cat # A10324-1
100 μg/vial

GPX5 Overview

Facts about Epididymal secretory glutathione peroxidase.

GPX5 3D structure. Source: alphafold

Epididymal secretory glutathione peroxidase (GPX5)

Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids.

Gene Information

Human
Gene Name:	GPX5
Uniprot:	O75715
Entrez:	2880

Family

Belongs to:

glutathione peroxidase family

Alternative Names

EC 1.11.1; EC 1.11.1.9; EGLP; epididymal androgen-related protein; epididymal secretory glutathione peroxidase; Epididymis-specific glutathione peroxidase-like protein; glutathione peroxidase 5 (epididymal androgen-related protein); Glutathione peroxidase 5; GPx-5; GSHPx-5

Molecular Weight

Mass (kDA):
25.202 kDA

Genomic Context


Human

Location:	6p22.1
Sequence:	6; NC_000006.12 (28525881..28534955)

Tissue Specificity

Epididymis.

Subcellular Localizations

Secreted.

Diseases

Neoplasms
Persistent Fetal Circulation Syndrome
Hangover From Alcohol
Neoplasm Metastasis
Metastatic Melanoma
Lung Neoplasms
Non-small Cell Lung Carcinoma
Male Infertility
Melanoma
Tumor Progression
Infertility

Malignant Neoplasm Of Lung
Dysplasia
Melanoma, Experimental
Hypertensive Disease
Multiple Myeloma
Malignant Neoplasms

Pathways

Fertilization
Spermatogenesis
Translation
Secretion
Photosynthesis
Protein Oxidation
Dna Repair
Protein Secretion
Response To Singlet Oxygen
Insemination
Localization
Sperm Motility
Cell Death

Cell Cycle
Acrosome Reaction
Mating
Regionalization
Pachytene
Mating Behavior
Photoprotection

PTMs

Reduction

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GPX5

References

PMID: 9639555 by Hall L., et al. The majority of human glutathione peroxidase type 5 (GPX5) transcripts are incorrectly spliced: implications for the role of GPX5 in the male reproductive tract.