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- Table of Contents
1 Citations 6 Q&As
Facts about Growth factor receptor-bound protein 7.
Plays a role in signal transduction in response to EGF. Plays a role in the regulation of cell proliferation and cell migration.
| Human | |
|---|---|
| Gene Name: | GRB7 |
| Uniprot: | Q14451 |
| Entrez: | 2886 |

| Belongs to: |
|---|
| GRB7/10/14 family |

B47; Epidermal growth factor receptor GRB-7; GRB7 adapter protein; GRB7; growth factor receptor-bound protein 7
Mass (kDA):
59.681 kDA

| Human | |
|---|---|
| Location: | 17q12 |
| Sequence: | 17; NC_000017.11 (39737938..39747285) |
Cytoplasm. Cell junction, focal adhesion. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic granule. Cell projection. Predominantly cytoplasmic. Detected in stress granules, where mRNA is stored under stress conditions.





PMID: 9125150 by Kishi T., et al. Molecular cloning of human GRB-7 co-amplified with CAB1 and c-ERBB-2 in primary gastric cancer.
PMID: 9710451 by Tanaka S., et al. A novel variant of human Grb7 is associated with invasive esophageal carcinoma.
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