GS homeobox 2 (Gsx2)

Throughout telencephalic development, causes ventralization of pallial progenitors and, depending on the developmental stage, specifies different neuronal fates. At early stages, sufficient and necessary to accurately define the ventral lateral ganglionic eminence (LGE) and its important derivatives, the striatal projection neurons.

At later stages, may specify LGE progenitors toward dorsal LGE fates, including olfactory bulb interneurons (PubMed:19709628). Transcription factor that binds 5'-CNAATTAG-3' DNA sequence (PubMed:7619729).