GUCY1A2 Antibodies

AND GUCY1A2 ELISA kits, GUCY1A2 Proteins

Many biological assays use antibodies to detect GUCY1A2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GUCY1A2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GUCY1A2 antibodies...

We validate the specificity of these antibodies to GUCY1A2 by testing them on tissues known to express GUCY1A2 positively and negatively. Browse below to find the GUCY1A2 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GUCY1A2 Infographic by Boster Bio

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GUCY1A2 Overview

Facts about Guanylate cyclase soluble subunit alpha-2.

GUCY1A2 3D structure. Source: alphafold

Guanylate cyclase soluble subunit alpha-2 (GUCY1A2)

Has guanylyl cyclase on binding to the beta-1 subunit. .

Gene Information

Human
Gene Name:	GUCY1A2
Uniprot:	P33402
Entrez:	2977

Family

Belongs to:

adenylyl cyclase class-4/guanylyl cyclase family

Alternative Names

Guanylate cyclase soluble subunit alpha-2

Molecular Weight

Mass (kDA):
81.75 kDA

Genomic Context


Human

Location:	11q22.3
Sequence:	11; NC_000011.10 (106674019..107018476, complement)

Tissue Specificity

Isoform 1 is expressed in fetal brain, liver, colon, endothelium and testis. Isoform 2 is expressed only in liver, colon and endothelium.

Subcellular Localizations

Cytoplasm.

Interacting Proteins

DLG1
SCRIB

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GUCY1A2

References

PMID: 1683630 by Harteneck C., et al. Molecular cloning and expression of a new alpha-subunit of soluble guanylyl cyclase. Interchangeability of the alpha-subunits of the enzyme.

PMID: 7673142 by Behrends S., et al. A variant of the alpha 2 subunit of soluble guanylyl cyclase contains an insert homologous to a region within adenylyl cyclases and functions as a dominant negative protein.