Guanylate kinase Antibodies

AND GUK1 ELISA kits, Guanylate kinase Proteins

Many biological assays use antibodies to detect Guanylate kinase, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Guanylate kinase in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Guanylate kinase antibodies...

We validate the specificity of these antibodies to Guanylate kinase by testing them on tissues known to express GUK1 positively and negatively. Browse below to find the GUK1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GUK1 Infographic by Boster Bio

All GUK1 Products

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Guanylate kinase (GUK1) (NM_000858) Human Recombinant Protein

Coomassie blue staining of purified GUK1 protein

$1249
Cat # PROTQ16774
20 µg

Anti-Guanylate kinase (GUK1) Mouse Monoclonal Antibody [Clone ID: OTI4A8]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY GUK1 (Right lane) cDNA for 48 hrs and lysed

Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-GUK1 mouse monoclonal antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-GUK1 mouse monoclonal antibody

Human, Mouse, Rat

Flow Cytometry, IHC, WB

$523
Cat # M10275
100 µl

Guanylate kinase (GUK1) (NM_000858) Human Over-expression Lysate

Guanylate kinase (GUK1) Human Over-expression Lysates NM_000858

Human

$628
Cat # LS002987
20 µg, 100 µg

GUK1 Overview

Facts about Guanylate kinase.

GUK1 3D structure. Source: alphafold

Guanylate kinase (GUK1)

Essential for recycling GMP and indirectly, cGMP. .

Gene Information

Human
Gene Name:	GUK1
Uniprot:	Q16774
Entrez:	2987

Family

Belongs to:

guanylate kinase family

Alternative Names

ATP:GMP Phosphotransferase; Deoxyguanylate Kinase; EC 2.7.4.8; FLJ42686; FLJ43710; GMK; GMP Kinase; Guanosine monophosphate Kinase; guanylate kinase 1; Guanylate Kinase; GUK1

Molecular Weight

Mass (kDA):
21.726 kDA

Genomic Context


Human

Location:	1q42.13
Sequence:	1; NC_000001.11 (228140084..228148984)

Subcellular Localizations

Photoreceptor inner segment. Cytoplasm, cytosol. Colocalizes with RD3 in photoreceptor inner segments and to a lesser extent in the outer plexiform layer.

Diseases

Neoplasms
Growth Hormone-secreting Pituitary Adenoma
Neoplasm Metastasis
Malignant Neoplasm Of Pituitary Gland
Cell Transformation, Neoplastic
Adenoma
Acth-secreting Pituitary Adenoma
Retinal Degeneration
Intracranial Neoplasm
Glioblastoma
Anaplastic Astrocytoma
Retinitis Pigmentosa

Brain Neoplasms
Carcinoma
Malignant Neoplasms
Metastatic Malignant Neoplasm To The Spinal Cord
Pituitary Adenoma
Headache
Pituitary Diseases

Pathways

Transport
Regeneration
Cell Junction Organization
Cell Growth
Phototransduction
Protein Transport
Localization
Excretion

Oncogenesis
Gdp-mannose Transport

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GUK1

References

PMID: 8647247 by Fitzgibbon J., et al. Human guanylate kinase (GUK1): cDNA sequence, expression and chromosomal localisation.

PMID: 8663313 by Brady W.A., et al. Cloning, characterization, and modeling of mouse and human guanylate kinases.