Histone H1.5 Antibodies

AND H1-5 ELISA kits, Histone H1.5 Proteins

Many biological assays use antibodies to detect Histone H1.5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Histone H1.5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Histone H1.5 antibodies...

We validate the specificity of these antibodies to Histone H1.5 by testing them on tissues known to express H1-5 positively and negatively. Browse below to find the H1-5 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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H1-5 Infographic by Boster Bio

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Histone H1.5 (HIST1H1B) (NM_005322) Human Over-expression Lysate

Human

$628
Cat # LS003009
20 µg, 100 µg

H1-5 Overview

Facts about Histone H1.5.

H1-5 3D structure. Source: alphafold

Histone H1.5 (H1-5)

Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers.

Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity). .

Gene Information

Human
Gene Name:	H1-5
Uniprot:	P16401
Entrez:	3009

Family

Belongs to:

histone H1/H5 family

Alternative Names

Histone H1.5

Molecular Weight

Mass (kDA):
22.58 kDA

Genomic Context


Human

Location:	6p22.1
Sequence:	6; NC_000006.12 (27866792..27867588, complement)

Tissue Specificity

Ubiquitous. Expressed in the majority of the cell lines tested and in testis.

Subcellular Localizations

Nucleus. Chromosome. According to PubMed:15911621 more commonly found in heterochromatin. According to PubMed:10997781 associates with actively transcribed chromatin and not heterochromatin.

Interacting Proteins

CBX8

PTMs

Acetylation
Citrullination

Hydroxylation
Methylation

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/H1-5

References

PMID: 9031620 by Albig W., et al. Characterization of the H1.5 gene completes the set of human H1 subtype genes.

PMID: 2613692 by Ohe Y., et al. Human spleen histone H1. Isolation and amino acid sequences of three minor variants, H1a, H1c, and H1d.