Histone H2B type 1-M Antibodies

AND H2BC14 ELISA kits, Histone H2B type 1-M Proteins

Many biological assays use antibodies to detect Histone H2B type 1-M, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Histone H2B type 1-M in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Histone H2B type 1-M antibodies...

We validate the specificity of these antibodies to Histone H2B type 1-M by testing them on tissues known to express H2BC14 positively and negatively. Browse below to find the H2BC14 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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H2BC14 Infographic by Boster Bio

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H2BC14 (NM_003521) Human Over-expression Lysate

Human

$628
Cat # LS008342
20 µg, 100 µg

H2BC14 Overview

Facts about Histone H2B type 1-M.

H2BC14 3D structure. Source: alphafold

Histone H2B type 1-M (H2BC14)

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.

Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Gene Information

Human
Gene Name:	H2BC14
Uniprot:	Q99879
Entrez:	8342

Family

Belongs to:

histone H2B family

Alternative Names

Histone H2B type 1-M

Molecular Weight

Mass (kDA):
13.989 kDA

Genomic Context


Human

Location:	6p22.1
Sequence:	6; NC_000006.12 (27815022..27815489)

Subcellular Localizations

Nucleus. Chromosome.

PTMs

Acetylation
ADP-ribosylation
Glycoprotein
Hydroxylation

Isopeptide bond
Methylation
Phosphoprotein
Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/H2BC14

References

PMID: 9439656 by Albig W., et al. The human histone gene cluster at the D6S105 locus.

PMID: 12757711 by Cheung W.L., et al. Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase.