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- Table of Contents
Facts about 2-hydroxyacyl-CoA lyase 1.
Human | |
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Gene Name: | HACL1 |
Uniprot: | Q9UJ83 |
Entrez: | 26061 |
Belongs to: |
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TPP enzyme family |
1600020H07Rik; 2,2-HPCL; 2-hydroxyacyl-CoA lyase 1; 2-hydroxyphytanoyl-CoA lyase2-hydroxyphytanol-CoA lyase; EC 4.1; HPCL; PHYH2FLJ55041; Phytanoyl-CoA 2-hydroxylase 2; phytanoyl-CoA hydroxylase 2
Mass (kDA):
63.729 kDA
Human | |
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Location: | 3p25.1 |
Sequence: | 3; NC_000003.12 (15560699..15601569, complement) |
Expressed in high levels in liver, also expressed in kidney, heart and skeletal muscle.
Peroxisome.
PMID: 10468558 by Foulon V., et al. Purification, molecular cloning, and expression of 2- hydroxyphytanoyl-CoA lyase, a peroxisomal thiamine hydrophosphate- dependent enzyme that catalyzes the carbon-carbon bond cleavage during alpha-oxidation of 3-methyl-branched fatty acids.